Description

4-Hydroxy-3,3,5,5-tetramethylcyclohexanone is a high-purity, functionalized cyclohexanone derivative, serving as a versatile and valuable intermediate in advanced organic synthesis. Its sterically hindered structure and hydroxyl-ketone functionality make it a critical building block for creating complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sterically hindered active pharmaceutical ingredients (APIs), including potential central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its structural motif can enhance stability and bioactivity.
• Fine Chemical & Fragrance Building Block: Employed in the synthesis of complex musk-like odorants and other high-value aroma chemicals due to its tetramethyl-substituted cyclohexane backbone.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for specialty polymers, coatings, and resins requiring specific thermal or mechanical properties.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Research & Development: A valuable standard and starting material in academic and industrial organic chemistry research for method development and novel compound libraries.

Basic Information

Product Name	4-Hydroxy-3,3,5,5-Tetramethylcyclohexanone
CAS No.	17429-06-0
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	3,3,5,5-Tetramethyl-4-cyclohexene-1-one-4-ol; 4-Hydroxy-3,3,5,5-tetramethylcyclohex-2-enone; Dihydroisophorone-4-ol; 4-Hydroxydihydroisophorone; 4-Hydroxy-2,2,6,6-tetramethylcyclohexanone; TMCH; Tetramethylcyclohexanone derivative
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3,3,5,5-tetramethylcyclohexanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specified range available
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.