Description

n-Carbobenzoxy-1,3-Diaminopropane Hydrochloride is a protected diamine derivative, primarily serving as a crucial building block in organic synthesis and peptide chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require high-purity intermediates for API synthesis and advanced material development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing diamine or polyamine structures.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected lysine or ornithine analog for introducing side-chain functionalities.
• Linker Chemistry: Employed in the development of bioconjugates, antibody-drug conjugates (ADCs), and polymer-drug conjugates due to its reactive amine groups.
• Chemical Biology Probes: Serves as a precursor for synthesizing molecular probes and tags used in biochemical and cellular studies.
• Polymer Modification: Utilized to introduce amine functionality into polymers, resins, and other materials for further chemical modification.
• Catalyst Ligand Synthesis: Acts as a starting material for preparing chiral ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	n-Carbobenzoxy-1,3-Diaminopropane Hydrochloride
CAS No.	17400-34-9
Molecular Formula	C12H19ClN2O2
Molecular Weight	258.74 g/mol
Synonyms	Nα-Cbz-1,3-diaminopropane hydrochloride; 1,3-Diaminopropane, N1-(phenylmethoxy)carbonyl-, monohydrochloride; N-Carbobenzoxy-1,3-propanediamine hydrochloride; Cbz-1,3-diaminopropane HCl; Z-1,3-Diaminopropane hydrochloride; Nα-Carbobenzyloxy-1,3-diaminopropane hydrochloride; (3-Amino-propyl)-carbamic acid benzyl ester hydrochloride; N1-(Benzyloxycarbonyl)-1,3-diaminopropane hydrochloride
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-1,3-Diaminopropane Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.