Description

Oxotremorine Sesquifumarate is a high-purity chemical compound, specifically the sesquifumarate salt of the potent muscarinic acetylcholine receptor agonist, oxotremorine. This compound is of significant value in neuroscience and pharmacological research for its role in studying cholinergic systems and as a tool compound in receptor binding assays. It is primarily needed by research institutions, pharmaceutical R&D departments, and contract research organizations (CROs) engaged in neuropharmacology, drug discovery, and the development of treatments for neurological disorders.

Application

• Pharmacological Research: Used as a selective muscarinic receptor agonist to study cholinergic neurotransmission and receptor function in vitro and in vivo.
• Neuroscience Tool Compound: Serves as a critical reference standard and active agent in experimental models of Parkinson's disease and other movement disorders.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and assay development for identifying and characterizing new muscarinic ligands or therapeutic candidates.
• Biochemical Studies: Utilized in receptor binding and enzyme inhibition studies to elucidate mechanisms of action and signal transduction pathways.
• Academic Research: A key reagent for university and institutional labs conducting fundamental research on the autonomic nervous system and cognitive functions.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	Oxotremorine Sesquifumarate
CAS No.	17360-35-9
Molecular Formula	C₁₄H₂₄N₂O₃ · 1.5C₄H₄O₄
Molecular Weight	Contact for details
Synonyms	Oxotremorine Sesquifumarate Salt; Oxotremorine Hemifumarate Hemihydrate (common misnomer); 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone Sesquifumarate; Oxotremorine Fumarate; LY 053-097; NSC 113001; Oxotremorine (as sesquifumarate)
EINECS	Contact for details

Quality Control

Our Oxotremorine Sesquifumarate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.