Description

3-Methyl-2-(Toluene-4-Sulfonylamino)-Butyric Acid is a specialized organic building block featuring a sulfonylamino-protected amino acid structure. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and bioactive peptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, peptidomimetics, and other small molecule drugs.
• Peptide Chemistry: Used in the preparation of modified amino acids and as a protecting group strategy in solid-phase peptide synthesis (SPPS).
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Material Science: Potential monomer or additive for creating specialized polymers with unique functional properties.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and asymmetric catalysis research.

Basic Information

Product Name	3-Methyl-2-(Toluene-4-Sulfonylamino)-Butyric Acid
CAS No.	17360-25-7
Molecular Formula	C12H17NO4S
Molecular Weight	271.33 g/mol
Synonyms	2-[(4-Methylphenyl)sulfonylamino]-3-methylbutanoic acid; N-(p-Toluenesulfonyl)-L-valine; N-Tosyl-L-valine; N-p-Tosyl-L-valine; L-Valine, N-[(4-methylphenyl)sulfonyl]-; (2S)-2-[(4-Methylbenzenesulfonyl)amino]-3-methylbutanoic acid; Tosyl-L-valine; 3-Methyl-2-(p-toluenesulfonylamino)butyric acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-(Toluene-4-Sulfonylamino)-Butyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.