Description

1-o-Methyl-2-(Acetylamino)-4-O,6-o-Benzylidene-2-Deoxy-α-D-Altropyranose CAS NO 17327-07-0 is a sophisticated, high-purity carbohydrate derivative featuring a benzylidene-protected sugar core. This compound is a critical chiral building block and synthetic intermediate for advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical industries for the development of novel therapeutics and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly nucleoside analogs and glycoconjugates.
• Glycochemistry Research: Used as a protected glycosyl donor or acceptor in the study and synthesis of oligosaccharides and glycoconjugates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting infectious diseases or cancer.
• Process Chemistry Development: Acts as a standard or starting material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Biochemical Tool Development: Utilized in the preparation of enzyme inhibitors, probes, or labeled compounds for biochemical assays and diagnostic applications.
• Academic & Institutional Research: A valuable reagent for universities and research institutes exploring carbohydrate chemistry, chemical biology, and new synthetic methodologies.

Basic Information

Product Name	1-o-Methyl-2-(Acetylamino)-4-O,6-o-Benzylidene-2-Deoxy-α-D-Altropyranose
CAS No.	17327-07-0
Molecular Formula	C₁₇H₂₁NO₆
Molecular Weight	335.35 g/mol
Synonyms	Methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-altropyranoside; 2-Acetamido-4,6-O-benzylidene-2-deoxy-α-D-altropyranose methyl glycoside; 1-O-Methyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-altropyranose; α-D-Altropyranose, 2-(acetylamino)-4,6-O-(phenylmethylene)-2-deoxy-, methyl glycoside; Benzylidene-protected D-altrosamine derivative; Methyl 2-acetamido-2-deoxy-4,6-O-(phenylmethylene)-α-D-altropyranoside
EINECS	Contact for details

Quality Control

Our production of 1-o-Methyl-2-(Acetylamino)-4-O,6-o-Benzylidene-2-Deoxy-α-D-Altropyranose adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.