Description

(25R)-5β-Spirostane-3β,6α,25-Triol CAS NO 17305-15-6 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and functional groups make it a valuable building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations related to steroid biosynthesis.
• Fine Chemical Synthesis: Employed as a chiral starting material for the production of complex, high-value specialty chemicals and advanced materials.
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	(25R)-5β-Spirostane-3β,6α,25-Triol
CAS No.	17305-15-6
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25R)-Spirostane-3β,6α,25-triol; 5β-Spirostane-3β,6α,25-triol, (25R)-; 3β,6α,25-Trihydroxy-5β-spirostane; (25R)-3β,6α,25-Trihydroxy-5β-spirostan; Tigogenin-3β,6α,25-triol (related derivative); Neotigogenin triol; Diosgenin analogue triol
EINECS	Contact for details

Quality Control

Every batch of (25R)-5β-Spirostane-3β,6α,25-Triol is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC and NMR. Our quality commitment ensures material suitable for GMP-grade pharmaceutical R&D and meets the stringent requirements for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.