Description

D-Penicillamine Acetone Adduct Hydrochloride is a specialized derivative of the amino acid penicillamine, formed as an adduct with acetone and presented as a hydrochloride salt. This compound is of significant value in pharmaceutical research and development, particularly as a key chiral intermediate or precursor in the synthesis of complex molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Asymmetric Synthesis: Utilized as a ligand or catalyst precursor in metal-catalyzed asymmetric reactions to create enantiomerically pure compounds.
• Research Chemical: Employed in academic and industrial R&D laboratories for studying reaction mechanisms and developing new synthetic methodologies.
• Chelating Agent Precursor: Acts as a starting material for the preparation of modified chelating agents used in metal sequestration or analytical chemistry.
• Bioconjugation Chemistry: Potential use in the modification of biomolecules due to the reactive functional groups present in the adduct structure.

Basic Information

Product Name	D-Penicillamine Acetone Adduct Hydrochloride
CAS No.	17266-78-3
Molecular Formula	C8H16ClNO2S
Molecular Weight	225.73 g/mol
Synonyms	D-3-Mercaptovaline Acetone Adduct Hydrochloride; (2R)-2-Amino-3-methyl-3-[(2-methylpropan-2-yl)sulfanyl]butanoic acid hydrochloride; D-Penicillamine Acetone Adduct HCl; (R)-2-Amino-3-methyl-3-((2-methyl-2-propanyl)thio)butanoic acid hydrochloride; D-β,β-Dimethylcysteine Acetone Adduct Hydrochloride; 2-Amino-3-methyl-3-[(1,1-dimethylethyl)thio]butanoic acid hydrochloride, (2R)-; Acetone Adduct of D-Penicillamine Hydrochloride
EINECS	Contact for details

Quality Control

Our D-Penicillamine Acetone Adduct Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles. Specifications can be aligned with research or cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.