Description

Spiro[2.2]Pent-1-Ylamine Hydrochloride is a high-purity, specialized organic building block featuring a unique strained spirocyclic structure. This compound is valued for its role as a key chiral intermediate and a rigid scaffold in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where its rigid structure can impart unique biological activity and stability.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of polymers with specific mechanical or optical properties.
• Chemical Biology Probe: Utilized in medicinal chemistry to explore structure-activity relationships (SAR) and for fragment-based drug discovery.
• Academic & Institutional Research: A valuable reagent for synthetic methodology development and studies in stereochemistry.

Basic Information

Product Name	Spiro[2.2]Pent-1-Ylamine Hydrochloride
CAS No.	17202-70-9
Molecular Formula	C6H10ClN
Molecular Weight	131.60 g/mol
Synonyms	Spiro[2.2]pentan-1-amine hydrochloride; 1-Aminospiro[2.2]pentane hydrochloride; Spiro[2.2]pent-1-ylamine hydrochloride; 1-Azaspiro[2.2]pentane hydrochloride; 1-Spiro[2.2]pentylamine hydrochloride; Spiro(pentane-1,1'-cyclopropan)-1-amine hydrochloride; Aminospiropentane HCl
EINECS	Contact for details

Quality Control

Our Spiro[2.2]Pent-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.