Description

4-Methoxybenzylamine Hydrochloride is a versatile aromatic amine hydrochloride salt, valued for its role as a key synthetic intermediate and building block in advanced organic synthesis. Its primary importance lies in introducing the 4-methoxybenzyl (PMB) protecting group and serving as a precursor for pharmaceuticals and fine chemicals. This compound is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the PMB protecting group.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a reagent for the introduction of the 4-methoxybenzyloxycarbonyl (Moz) protecting group in peptide synthesis.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel molecular entities.

Basic Information

Product Name	4-Methoxybenzylamine Hydrochloride
CAS No.	17061-61-9
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	p-Methoxybenzylamine Hydrochloride; (4-Methoxyphenyl)methanamine Hydrochloride; 4-Methoxybenzenemethanamine Hydrochloride; PMB-NH2·HCl; Anisylamine Hydrochloride; 4-Anisylamine Hydrochloride; 4-Methoxybenzylammonium Chloride
EINECS	241-137-5

Quality Control

Our 4-Methoxybenzylamine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	248°C - 252°C
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.