Description

3-(2,5-Dioxo-2,5-Dihydro-Pyrrol-1-Yl)-Benzoic Acid is a high-purity chemical intermediate featuring a maleimide group linked to a benzoic acid moiety, enabling versatile bioconjugation and polymer modification. This compound is critical for researchers and manufacturers requiring precise, reliable building blocks for advanced material synthesis and pharmaceutical development. It is primarily utilized in the production of specialty polymers, bioconjugates, and as a key reagent in proteomics and antibody-drug conjugate (ADC) research.

Application

• Bioconjugation Reagent: Used for site-specific labeling of proteins, peptides, and antibodies via thiol-maleimide chemistry.
• Polymer Modification: Serves as a functional monomer or crosslinker for synthesizing smart polymers, hydrogels, and responsive materials.
• Pharmaceutical Intermediate: A key building block in the synthesis of targeted therapeutics, including Antibody-Drug Conjugates (ADCs).
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and other chemical proteomics applications.
• Surface Functionalization: Used to create maleimide-activated surfaces for biosensor chips, microarray slides, and diagnostic devices.
• Material Science: Incorporated into coatings and composites to introduce specific chemical functionality and reactivity.

Basic Information

Product Name	3-(2,5-Dioxo-2,5-Dihydro-Pyrrol-1-Yl)-Benzoic Acid
CAS No.	17057-07-7
Molecular Formula	C11H7NO4
Molecular Weight	217.18 g/mol
Synonyms	3-Maleimidobenzoic Acid; 1H-Pyrrole-2,5-dione, 1-(3-carboxyphenyl)-; 3-(Maleimido)benzoic Acid; m-Maleimidobenzoic Acid; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic Acid; 3-(2,5-Dioxopyrrolidin-1-yl)benzoic Acid; Benzoic acid, 3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-; 17057-07-7
EINECS	241-148-2

Quality Control

Our 3-(2,5-Dioxo-2,5-Dihydro-Pyrrol-1-Yl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.