Description

N'-[7-(125I)Iodoquinolin-4-Yl]-N,n-Dimethylpropane-1,3-Diamine is a specialized iodinated quinoline derivative, a key intermediate in the development of radiopharmaceuticals and diagnostic agents. Its core value lies in its role as a precursor for radiolabeling with iodine-125, enabling precise imaging and research applications in nuclear medicine. This compound is essential for pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers focused on oncology, neurology, and cardiology tracer development.

Application

• Radiopharmaceutical Precursor: Primary intermediate for synthesizing iodine-125 (125I) labeled diagnostic tracers and therapeutic agents.
• Molecular Imaging Probes: Used in the development of SPECT (Single-Photon Emission Computed Tomography) imaging agents for cancer detection and monitoring.
• Research Chemical: Serves as a critical reagent in academic and industrial laboratories studying receptor binding, pharmacokinetics, and biodistribution.
• Diagnostic Kit Manufacturing: A key building block for companies producing kits for in-vitro diagnostics and radioimmunoassays (RIA).
• Tracer Synthesis for Neurology: Potential use in creating ligands for imaging neurological targets and studying brain function.
• Pre-clinical Drug Development: Employed in the discovery and evaluation stages of novel targeted radiotherapeutics.

Basic Information

Product Name	N'-[7-(125I)Iodoquinolin-4-Yl]-N,n-Dimethylpropane-1,3-Diamine
CAS No.	17033-82-8
Molecular Formula	C14H19IN3
Molecular Weight	348.23 g/mol
Synonyms	7-Iodo-N-[3-(dimethylamino)propyl]quinolin-4-amine; N1-[7-Iodo-4-quinolyl]-N3,N3-dimethyl-1,3-propanediamine; IQNP precursor; (125I)IQNP ligand precursor; 4-Amino-7-iodoquinoline N-(3-dimethylaminopropyl) derivative; 7-Iodo-4-quinolylamine propyl dimethylamine; 17033-82-8; IQNP analogue
EINECS	Contact for details

Quality Control

This high-purity intermediate is produced under strict quality control protocols suitable for pharmaceutical R&D. Each batch is characterized to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing parameters such as radiochemical purity (by HPLC), specific activity, and chemical purity. Our manufacturing aligns with cGMP principles where applicable for non-radioactive precursor synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. For long-term stability, consider storage at -20°C under an inert atmosphere. This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Chemical Purity	≥ 98%
Specific Activity	Contact for details
Radiochemical Purity	≥ 95%
Solubility	Soluble in DMSO, ethanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.