Description

L-Leucinol is a valuable non-natural amino alcohol derivative, serving as a versatile chiral building block in advanced organic synthesis. Its significance lies in its ability to introduce the hydrophobic leucine side chain moiety while providing both amino and hydroxyl functional groups for further chemical modification. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing peptide mimetics, active pharmaceutical ingredients (APIs), and novel chiral ligands or catalysts.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the synthesis of protease inhibitors, antiviral drugs, and other bioactive molecules.
• Peptidomimetics & Drug Discovery: Used to construct non-peptide scaffolds that mimic peptide structure and function, improving metabolic stability.
• Asymmetric Catalysis: Employed as a precursor for chiral auxiliaries, ligands, and organocatalysts in enantioselective reactions.
• Fine Chemical Synthesis: Building block for specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and bioconjugation probes due to its bifunctional nature.
• Academic & Industrial Research: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	L-Leucinol
CAS No.	17016-87-4
Molecular Formula	C6H15NO
Molecular Weight	117.19 g/mol
Synonyms	(S)-2-Amino-4-methyl-1-pentanol; (S)-Leucinol; L-2-Amino-4-methylpentan-1-ol; (S)-(-)-2-Amino-4-methyl-1-pentanol; H-Leu-ol; L-Leucinol; (2S)-2-Amino-4-methylpentan-1-ol; 1-Pentanol, 2-amino-4-methyl-, (S)-
EINECS	241-087-4

Quality Control

Our L-Leucinol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results for identity, purity, and chiral purity. Our quality commitment aligns with the standards required for pharmaceutical research and development. Specifications and documentation can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.