Description

3-tert-Butyl-4-Hydroxyacetophenone is a specialized phenolic ketone compound with significant utility as a key intermediate in organic synthesis. Its molecular structure, featuring both a tert-butyl group and a hydroxyacetophenone moiety, makes it a valuable precursor for the development of advanced materials and fine chemicals. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel antioxidants, UV stabilizers, or active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring phenolic antioxidant properties.
• Polymer Additive Precursor: Used in the manufacture of high-performance antioxidants and light stabilizers for plastics, resins, and synthetic rubbers to prevent thermal and UV degradation.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain pesticides and herbicides, where its phenolic structure contributes to biological activity.
• Fine Chemical Production: Employed in organic synthesis for creating complex molecules used in flavors, fragrances, and specialty dyes.
• Research & Development: A valuable reference standard and starting material in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-tert-Butyl-4-Hydroxyacetophenone
CAS No.	16928-01-1
Molecular Formula	C₁₂H₁₆O₂
Molecular Weight	192.26 g/mol
Synonyms	1-(4-Hydroxy-3-tert-butylphenyl)ethanone; 4'-Hydroxy-3'-tert-butylacetophenone; 3-tert-Butyl-4-hydroxyacetophenone; 3-(1,1-Dimethylethyl)-4-hydroxyacetophenone; 4-Acetyl-2-tert-butylphenol; BHAP; Butylhydroxyacetophenone; NSC 163082
EINECS	240-985-5

Quality Control

Our 3-tert-Butyl-4-Hydroxyacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and residual solvent analysis, to ensure it meets exacting standards for use in sensitive applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.