Description

1-o-Methyl-2-O,3-o-Dibenzyl-6-o-(Triphenylmethyl)-L-Altrofuranose CAS NO 16895-95-7 is a sophisticated, multi-protected carbohydrate derivative, specifically an L-altrofuranose sugar building block. This compound is critically important as a key chiral intermediate in the synthesis of complex nucleoside analogs, antiviral agents, and other high-value pharmaceutical actives. It is primarily required by research institutions and pharmaceutical development companies engaged in nucleoside chemistry and the production of antiviral drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of novel nucleoside-based antiviral and anticancer agents.
• Antiviral Drug Development: Used in research and production of experimental therapeutics targeting viruses such as HIV, hepatitis, and herpes.
• Nucleoside Chemistry Research: A valuable tool for academic and industrial chemists studying carbohydrate chemistry, stereoselective glycosylation, and protecting group strategies.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Glycobiology & Glycochemistry: Acts as a building block for synthesizing complex oligosaccharides or glycomimetics for biological studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) specializing in custom synthesis of advanced intermediates.

Basic Information

Product Name	1-o-Methyl-2-O,3-o-Dibenzyl-6-o-(Triphenylmethyl)-L-Altrofuranose
CAS No.	16895-95-7
Molecular Formula	C36H36O6
Molecular Weight	564.67 g/mol
Synonyms	1-O-Methyl-2,3-di-O-benzyl-6-O-trityl-α-L-altrofuranose; 6-O-Trityl-1-O-methyl-2,3-di-O-benzyl-α-L-altrofuranose; L-Altrofuranose, 1-O-methyl-2,3-di-O-benzyl-6-O-trityl-; 1-Methyl-2,3-dibenzyl-6-trityl-α-L-altrofuranose; Protected L-Altrofuranose Derivative; Trityl-Protected Altrose Derivative; Benzyl-Protected Altrose Methyl Glycoside
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to confirm identity and quality. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a desiccated environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.