Description

1,2-o-Cyclohexylidene-α-D-Glucofuranose is a protected carbohydrate derivative, specifically a glucofuranose acetal, that serves as a crucial chiral building block and synthetic intermediate. Its primary value lies in providing a stable, non-participating protecting group for the 1,2-diol system, enabling selective functionalization at other hydroxyl positions during complex organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for the production of nucleosides, antibiotics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material or chiral synthon in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Fundamental building block for constructing complex oligosaccharides, glycoconjugates, and glycomimetics in academic and industrial R&D.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances where stereochemical control is paramount.
• Agrochemical Development: Intermediate in the production of advanced, biologically active compounds for crop protection.
• Glycobiology Tools: Serves as a precursor for labeled sugars or probes used in studying biological recognition processes.

Basic Information

Product Name	1,2-o-Cyclohexylidene-α-D-Glucofuranose
CAS No.	16832-21-6
Molecular Formula	C₁₂H₂₀O₆
Molecular Weight	260.28 g/mol
Synonyms	1,2-O-Cyclohexylidene-α-D-glucofuranose; α-D-Glucofuranose, 1,2-O-cyclohexylidene-; 1,2:5,6-Di-O-cyclohexylidene-α-D-glucofuranose (common misnomer, often used in searches); Cyclohexylidene-protected glucose; D-Glucose, 1,2-O-(1-methylethylidene)- (related compound); 1,2-Cyclohexylidene-α-D-glucofuranose; Acetal-protected glucofuranose; Chiral acetal of D-glucose.
EINECS	240-868-9

Quality Control

Our 1,2-o-Cyclohexylidene-α-D-Glucofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-20° to -25° (c=1 in H₂O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.