Description

(1S)-1,4Aβ-Dimethyl-6-Methoxy-1,2,3,4,4A,9,10,10Aα-Octahydrophenanthrene-1β-Carbaldehyde is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure makes it a valuable building block for the construction of intricate molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of complex drug candidates, particularly those with steroidal or terpenoid-like frameworks.
• Organic Synthesis Research: Used in academic and industrial laboratories to develop new synthetic methodologies, such as cyclization reactions or stereoselective transformations.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, including advanced materials, ligands for catalysis, and fragrances.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent quality and reliable supply.

Basic Information

Product Name	(1S)-1,4Aβ-Dimethyl-6-Methoxy-1,2,3,4,4A,9,10,10Aα-Octahydrophenanthrene-1β-Carbaldehyde
CAS No.	16826-83-8
Molecular Formula	C₁₈H₂₄O₂
Molecular Weight	272.38 g/mol
Synonyms	(1S)-1,4Aβ-Dimethyl-6-methoxy-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1β-carboxaldehyde; (1S,4aS,10aR)-1,4a-Dimethyl-6-methoxy-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carbaldehyde; 1,4aβ-Dimethyl-6-methoxy-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1β-carboxaldehyde; Light-sensitive (store away from light) intermediate; Octahydrophenanthrene carbaldehyde derivative.
EINECS	Contact for details

Quality Control

Our (1S)-1,4Aβ-Dimethyl-6-Methoxy-1,2,3,4,4A,9,10,10Aα-Octahydrophenanthrene-1β-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect against moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.