Description

Blood Group H Disaccharide [Fuc-Alpha1-2)Gal] is a defined carbohydrate antigen crucial for immunological and biochemical research. This compound serves as the core structural determinant for the H antigen, the biosynthetic precursor to the ABO blood group system. It is an essential reagent for scientists in glycobiology, immunology, and diagnostic development, enabling the study of carbohydrate-protein interactions, blood typing mechanisms, and the development of novel therapeutics and diagnostics.

Application

• Glycobiology Research: A fundamental tool for studying glycosyltransferase activity, carbohydrate-protein interactions, and biosynthetic pathways of blood group antigens.
• Immunological Assay Development: Used as a coating antigen or inhibitor in ELISA, SPR (Surface Plasmon Resonance), and other assays to detect and characterize anti-H or related antibodies.
• Diagnostic Reagent Synthesis: Serves as a key intermediate or standard in the production of reagents for blood typing and related clinical diagnostics.
• Enzyme Substrate: Acts as a specific substrate for α-1,2-fucosyltransferases and other enzymes involved in oligosaccharide synthesis.
• Bioconjugation & Probe Development: Utilized for the synthesis of neoglycoconjugates, glycodendrimers, or fluorescent probes to study cell surface recognition events.
• Vaccine & Therapeutic Research: Investigated for its role in the development of carbohydrate-based vaccines and anti-adhesion therapies targeting pathogen binding.
• Quality Control Standard: Employed as a reference standard in the quality control of blood group-related diagnostic kits and biochemicals.

Basic Information

Item	Detail
Product Name	Blood Group H Disaccharide [Fuc-Alpha1-2)Gal]
CAS No.	16741-18-7
Molecular Formula	C12H22O10
Molecular Weight	326.30 g/mol
Synonyms	α-L-Fuc-(1→2)-D-Gal; 2'-Fucosyllactose (isomer); H Disaccharide; Fucosyl-alpha(1-2)galactose; L-Fucose α1-2 D-Galactose; Blood group H type 2 trisaccharide precursor; 2-O-α-L-Fucopyranosyl-D-galactopyranose
EINECS	Contact for details

Quality Control

Our Blood Group H Disaccharide is produced under stringent conditions to ensure high purity and batch-to-batch consistency, critical for research reproducibility. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact us.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Rotation	Contact for details
Water Content (KF)	< 5.0 %
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.