Description

8-Hydroxy-6-Nitroquinoline is a versatile nitro-substituted quinoline derivative that serves as a critical synthetic intermediate and functional building block. Its unique structure, combining a hydroxyl group with a nitro moiety on the quinoline scaffold, makes it valuable for constructing complex molecules with specific electronic and binding properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antimicrobial and anticancer agents.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and plant growth regulators due to its bioactive quinoline core.
• Coordination Chemistry & Ligand Synthesis: Acts as a chelating agent for metal ions, useful in creating catalysts and metal-organic frameworks (MOFs).
• Dye & Pigment Manufacturing: Intermediate for producing nitroquinoline-based dyes and colorants.
• Organic Synthesis Building Block: Employed in heterocyclic chemistry for constructing more complex nitrogen-containing compounds.
• Analytical Reagent: Potential use as a reagent or standard in analytical chemistry and spectroscopy.

Basic Information

Product Name	8-Hydroxy-6-Nitroquinoline
CAS No.	16727-28-9
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	6-Nitro-8-quinolinol; 6-Nitro-8-hydroxyquinoline; 8-Hydroxy-6-nitro-quinoline; 8-Quinolinol, 6-nitro-; 6-Nitro-8-quinolol; NSC 403697; 6-Nitrooxine
EINECS	240-787-8

Quality Control

Our 8-Hydroxy-6-Nitroquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.