Description

(+)-cis-Dioxolane CAS NO 16709-43-6 is a high-purity, chiral cyclic acetal characterized by its specific stereochemistry. This compound serves as a versatile and valuable chiral building block and solvent in advanced synthetic chemistry. It is primarily utilized by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex, optically active molecules.

Application

• Chiral Auxiliary and Building Block: Key intermediate in the asymmetric synthesis of pharmaceuticals, including active pharmaceutical ingredients (APIs) and fine chemicals.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of ligands for metal-catalyzed reactions to induce enantioselectivity.
• Specialty Solvent: Employed as a polar aprotic solvent for sensitive reactions where its specific stereochemistry and purity are critical.
• Flavor and Fragrance Synthesis: Intermediate in the production of enantiomerically pure aroma chemicals and flavor compounds.
• Polymer Chemistry: Monomer or modifying agent for creating polymers with specific stereoregular structures.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides with targeted activity.

Basic Information

Product Name	(+)-cis-Dioxolane
CAS No.	16709-43-6
Molecular Formula	C3H6O2
Molecular Weight	74.08 g/mol
Synonyms	(+)-cis-1,3-Dioxolane; (4R,5S)-1,3-Dioxolane; (R)-(+)-cis-1,3-Dioxolane; (R)-(+)-4,5-Dimethyl-1,3-dioxolane; cis-4,5-Dimethyl-1,3-dioxolane; (4R,5S)-4,5-Dimethyl-1,3-dioxolane; Dioxolane, (+)-cis-; Optically active cis-dioxolane
EINECS	240-764-7

Quality Control

Every batch of (+)-cis-Dioxolane is produced and analyzed under strict quality management protocols to ensure identity, purity, and enantiomeric excess meet exacting standards. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation [α]D20	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.