Description

(2R)-2-(Acetylamino)-2-Phenylpropionic Acid CAS NO 16707-49-6 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. Its value lies in its well-defined stereochemistry, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular configuration dictates biological activity and product efficacy.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Used in the development of novel chiral catalysts and ligands for stereoselective chemical transformations.
• Agrochemical Research: Serves as a chiral synthon in the development of new herbicides, fungicides, and insecticides with improved selectivity and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reference standard and starting material for research in organic chemistry, medicinal chemistry, and process development.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and mimetics for biochemical and pharmacological studies.

Basic Information

Product Name	(2R)-2-(Acetylamino)-2-Phenylpropionic Acid
CAS No.	16707-49-6
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(R)-2-Acetamido-2-phenylpropionic Acid; (R)-N-Acetyl-α-methylphenylglycine; D-N-Acetyl-α-methylphenylglycine; (2R)-2-Acetamido-2-phenylpropanoic Acid; (R)-α-Methyl-N-acetylphenylglycine; N-Acetyl-D-α-methylphenylglycine; (R)-2-(Acetylamino)-2-phenylpropanoic Acid; Ac-D-α-MePhg-OH
EINECS	Contact for details

Quality Control

Our (2R)-2-(Acetylamino)-2-Phenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.