Description

3,4,6-Tri-o-Benzyl-β-D-Mannopyranose-1,2-(Methyl Orthoacetate) is a key protected carbohydrate intermediate, specifically a mannose derivative with benzyl and orthoester protecting groups. This compound matters because it provides a versatile and reactive scaffold for the controlled synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research chemists and process development scientists in the pharmaceutical and biotechnology industries for the production of novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycosylation Reactions: Serves as a crucial mannosyl donor in the stereoselective synthesis of oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: A building block for creating glycoproteins, glycolipids, and other biologically active conjugates for vaccine development.
• Chemical Biology Probes: Employed in the synthesis of labeled sugars and probes to study carbohydrate-protein interactions and metabolic pathways.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring mannose motifs.
• Academic & Industrial R&D: A fundamental reagent for exploring new synthetic methodologies and carbohydrate chemistry in both university and corporate laboratories.

Basic Information

Product Name	3,4,6-Tri-o-Benzyl-β-D-Mannopyranose-1,2-(Methyl Orthoacetate)
CAS No.	16697-49-7
Molecular Formula	C30H34O7
Molecular Weight	506.59 g/mol
Synonyms	Methyl 3,4,6-Tri-O-benzyl-α-D-mannopyranoside 1,2-(Methyl Orthoacetate); 1,2-O-(1-Methoxyethylidene)-3,4,6-tri-O-benzyl-α-D-mannopyranose; 3,4,6-Tri-O-benzyl-1,2-O-(1-methoxyethylidene)-α-D-mannopyranose; Tri-O-benzyl-mannose orthoacetate; Mannose, 3,4,6-tris-O-(phenylmethyl)-, methyl 1,2-(methyl orthoacetate), α-D-; Protected Mannose Orthoester; Benzylated Mannose Orthoacetate Derivative
EINECS	Contact for details

Quality Control

Our 3,4,6-Tri-o-Benzyl-β-D-Mannopyranose-1,2-(Methyl Orthoacetate) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic chemistry applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.