Description

1-Chloro-3-Nitro-Propane is a versatile halogenated nitroalkane building block used in organic synthesis. This compound is valued for its bifunctional reactivity, where the chloro and nitro groups serve as handles for nucleophilic substitution and reduction reactions, respectively. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing amine or aminoalkyl functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators, leveraging its reactivity to form heterocyclic compounds.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to introduce 3-nitropropyl groups or as a substrate for reduction to yield γ-aminopropyl derivatives.
• Polymer & Resin Modifier: Acts as a cross-linking agent or a functional monomer in the production of specialty polymers and epoxy resins.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	1-Chloro-3-Nitro-Propane
CAS No.	16694-52-3
Molecular Formula	C₃H₆ClNO₂
Molecular Weight	123.54 g/mol
Synonyms	3-Nitro-1-chloropropane; 3-Nitropropyl chloride; γ-Nitropropyl chloride; 1-Chloro-3-nitropropane; NSC 8817; Chloronitropropane; Nitrochloropropane
EINECS	240-763-7

Quality Control

Our 1-Chloro-3-Nitro-Propane is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. The container should be kept tightly closed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.28 - 1.32 g/mL
Refractive Index (n20D)	1.450 - 1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.