Description

3-(131I)Iodo-L-Tyrosine is a radiolabeled amino acid derivative where the radioactive iodine isotope I-131 is incorporated into the L-tyrosine structure. This compound is critical for research and development in nuclear medicine, particularly for studying thyroid metabolism, amino acid transport, and as a potential precursor for targeted radiopharmaceuticals. It serves the essential needs of radiochemists, pharmaceutical researchers, and diagnostic developers working in oncology, endocrinology, and molecular imaging.

Application

• Radiopharmaceutical Research & Development: Acts as a key intermediate or reference standard in the synthesis of novel iodine-131 labeled diagnostic and therapeutic agents.
• Metabolic Pathway Studies: Used as a tracer to investigate tyrosine metabolism, protein synthesis rates, and thyroid hormone biosynthesis in preclinical models.
• Targeted Radionuclide Therapy (TRT) Development: Explored as a building block for creating compounds that deliver I-131 specifically to cancer cells, such as in neuroendocrine tumors.
• In Vitro & Cell-Based Assays: Utilized in research to study amino acid transporter function and cellular uptake mechanisms.
• Quality Control & Reference Standard: Serves as an analytical standard for HPLC or radio-TLC to validate the purity and identity of other radiopharmaceutical batches.
• Educational & Method Development: Employed in academic and industrial labs for training in radiochemical handling and developing new radiolabeling techniques.

Basic Information

Item	Detail
Product Name	3-(131I)Iodo-L-Tyrosine
CAS No.	16624-40-1
Molecular Formula	C9H10131INO3
Molecular Weight	Contact for details
Synonyms	L-3-[131I]Iodotyrosine; 3-Iodo-L-tyrosine-131I; (131I)-3-Iodo-L-tyrosine; Radioiodinated L-tyrosine; I-131 Labeled L-Tyrosine; 3-(131I)Iodotyrosine; L-Tyrosine, 3-iodo-, labeled with iodine-131; [131I]ITYR
EINECS	Contact for details

Quality Control

Every batch of 3-(131I)Iodo-L-Tyrosine is produced and tested under strict quality management systems. We ensure high radiochemical purity and specific activity through analytical methods including radio-HPLC and radio-TLC. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing radionuclidic purity, radiochemical purity, specific activity, and solvent content. Our quality commitment aligns with cGMP principles for investigational radiopharmaceuticals.

Storage

Preserve in a tightly closed container, protected from light. This material is strictly light-sensitive (protect from all light exposure). Store at the recommended temperature (typically 2-8°C or as specified on the COA) in an appropriate shielded container to minimize radiation exposure. The product is for research use only and must be handled by trained personnel in compliance with all local and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Radionuclidic Identity (Gamma Spectroscopy)	I-131
Radiochemical Purity (Radiometric HPLC/TLC)	≥ 95%
Specific Activity	Contact for details
Chemical Purity (HPLC)	Contact for details
pH	3.0 - 7.0
Solvent	Ethanol/Water or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.