Description

4-Bromo-1-Chloro-2-Nitrobenzene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for research and development chemists and production facilities specializing in active pharmaceutical ingredients (APIs), specialty dyes, and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the nitro and halogen groups are integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing complex azo dyes and other colored compounds.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro and halogen groups make it highly reactive in SNAr reactions for introducing various nucleophiles.

Basic Information

Product Name	4-Bromo-1-Chloro-2-Nitrobenzene
CAS No.	16588-24-2
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	1-Bromo-4-Chloro-2-Nitrobenzene; 2-Nitro-4-Bromochlorobenzene; 4-Bromo-2-Nitrochlorobenzene; 4-Chloro-1-Bromo-2-Nitrobenzene; p-Chloro-o-nitro-bromobenzene; NSC 404083; 16588-24-2
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Chloro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and GC-MS, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.