Description

6-(Trifluoromethyl)Quinazolin-4(3H)-One is a high-value, fluorinated quinazolinone derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group on the quinazolinone core, imparts desirable physicochemical properties to target molecules, making it essential for research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of potential drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components or specialty polymers.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	6-(Trifluoromethyl)Quinazolin-4(3H)-One
CAS No.	16544-67-5
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	4(3H)-Quinazolinone, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-4(3H)-quinazolinone; 6-Trifluoromethylquinazolin-4(3H)-one; 6-Trifluoromethyl-4-hydroxyquinazoline; 6-Trifluoromethyl-3,4-dihydro-4-oxoquinazoline; 6-Trifluoromethyl-4-quinazolinol; 6-Trifluoromethyl-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.