Description

2-Chloroacrylamide is a versatile halogenated acrylamide derivative serving as a critical reactive intermediate in advanced organic synthesis. Its primary value lies in its bifunctional reactivity, featuring both an electron-deficient double bond and an amide group, enabling its use in polymerization and cross-linking reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it is utilized to introduce functional handles or modify material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Polymer & Resin Modification: Acts as a co-monomer or cross-linking agent to impart specific characteristics like hydrophilicity or reactivity to acrylic polymers and coatings.
• Bioconjugation & Probe Synthesis: Useful in biochemical research for labeling proteins or nucleic acids due to its reactive chloro and amide groups.
• Organic Synthesis Reagent: Employed in Michael addition reactions and other nucleophilic attacks for constructing complex organic molecules.
• Hydrogel Production: A component in the synthesis of stimuli-responsive or superabsorbent hydrogels for medical and industrial applications.

Basic Information

Product Name	2-Chloroacrylamide
CAS No.	16490-68-9
Molecular Formula	C3H4ClNO
Molecular Weight	105.52 g/mol
Synonyms	2-Chloro-2-propenamide; Acrylamide, 2-chloro-; 2-Propenamide, 2-chloro-; NSC 401123; α-Chloroacrylamide; (Chloromethylene)acetamide; 2-Chloroacrylic acid amide
EINECS	240-553-4

Quality Control

Our 2-Chloroacrylamide is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	74 - 78 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.