Description

Ethyl 5-Amino-1-(2-Nitrophenyl)-1H-Pyrazole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct pyrazole core structure. This compound matters because it serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic & R&D: Utilized in university and institutional laboratories for research into heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	Ethyl 5-Amino-1-(2-Nitrophenyl)-1H-Pyrazole-4-Carboxylate
CAS No.	16459-33-9
Molecular Formula	C12H12N4O4
Molecular Weight	276.25 g/mol
Synonyms	5-Amino-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 5-amino-1-(o-nitrophenyl)-1H-pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 5-amino-1-(2-nitrophenyl)-, ethyl ester; 16459-33-9; 5-Amino-1-(2-nitrophenyl)pyrazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Amino-1-(2-Nitrophenyl)-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.