Description

n-Acetyl-3-Sulfonamoyl-L-Alanine Methyl Ester is a specialized, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmaceutical agents and bioactive molecules, particularly those targeting enzyme inhibition. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex sulfonamide-containing compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) with sulfonamide pharmacophores.
• Medicinal Chemistry Research: Used as a building block for constructing compound libraries in drug discovery programs targeting various enzymes.
• Process Development: Serves as a standard or reference material in the optimization of synthetic routes for scale-up production.
• Biochemical Tool Compound: Potential use in studying enzyme mechanisms and interactions where a modified alanine residue is required.
• Peptidomimetic Synthesis: Incorporated into peptide analogs to enhance stability, bioavailability, or biological activity.

Basic Information

Product Name	n-Acetyl-3-Sulfonamoyl-L-Alanine Methyl Ester
CAS No.	16435-47-5
Molecular Formula	C7H12N2O5S
Molecular Weight	236.25 g/mol
Synonyms	Methyl N-acetyl-3-sulfamoyl-L-alaninate; L-Alanine, N-acetyl-3-(aminosulfonyl)-, methyl ester; Acetyl-3-sulfamoylalanine methyl ester; N-Acetyl-3-sulfamoyl-L-alanine methyl ester; Methyl (2S)-2-acetamido-3-sulfamoylpropanoate; 3-Sulfamoyl-N-acetyl-L-alanine methyl ester; (S)-Methyl 2-acetamido-3-sulfamoylpropanoate
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Sulfonamoyl-L-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.