Description

3-(2-Propynyl)Quinazolin-4(3H)-One is a specialized heterocyclic organic compound belonging to the quinazolinone class, serving as a crucial synthetic intermediate and building block in advanced chemical research. Its unique structure, featuring a propynyl side chain, makes it a valuable precursor for developing novel pharmacologically active molecules and functional materials. This high-purity compound is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for lead optimization and new chemical entity synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions.
• Academic & R&D: Fundamental research in organic synthesis methodologies and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	3-(2-Propynyl)Quinazolin-4(3H)-One
CAS No.	16347-56-1
Molecular Formula	C₁₁H₈N₂O
Molecular Weight	184.20 g/mol
Synonyms	3-(Prop-2-yn-1-yl)quinazolin-4(3H)-one; 3-Propargyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-(2-propynyl)-; 3-(Prop-2-ynyl)quinazolin-4-one; 3-(Prop-2-yn-1-yl)-3,4-dihydroquinazolin-4-one; Propargyl Quinazolinone; 3-Propargylquinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Propynyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.