Description

Ethylisopropylnitrosamine is a specialized nitrosamine compound of significant interest in chemical research and industrial applications. Its primary value lies in its utility as a key intermediate and reference standard in analytical chemistry and toxicology studies. This product is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity chemical building blocks and analytical markers.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration and validation of analytical methods, particularly in the detection and quantification of nitrosamine impurities in pharmaceuticals and consumer products.
• Pharmaceutical Research: Serves as a critical intermediate or a model compound in the research and development of novel therapeutic agents and in studies of metabolic pathways.
• Toxicological Studies: Employed in laboratory research to investigate the carcinogenic potential, metabolic activation, and DNA adduct formation of nitrosamine compounds.
• Chemical Synthesis: Acts as a specialized building block or reagent in organic synthesis for the preparation of more complex molecules in research settings.
• Quality Assurance & Control: Utilized by QA/QC laboratories to develop, optimize, and verify analytical procedures like HPLC-MS/MS and GC-MS for trace impurity analysis.
• Regulatory Compliance Testing: Essential for testing laboratories to ensure drug substances and products comply with stringent global regulatory limits for nitrosamine impurities (e.g., EMA, FDA, ICH M7).

Basic Information

Product Name	Ethylisopropylnitrosamine
CAS No.	16339-04-1
Molecular Formula	C5H12N2O
Molecular Weight	116.16 g/mol
Synonyms	N-Nitrosoethylisopropylamine; N-Ethyl-N-nitroso-2-propanamine; N-Ethyl-N-nitrosoisopropylamine; N-Nitroso-N-ethylisopropylamine; Isopropyl ethyl nitrosamine; EINECS 240-394-1; 2-Propanamine, N-ethyl-N-nitroso-
EINECS	240-394-1

Quality Control

Our Ethylisopropylnitrosamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and determination of related substances and residual solvents to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified purity criteria.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between 2°C and 8°C. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.