Description

(+/-)-trans-1,3-Cyclopentanediol CAS NO 16326-98-0 is a versatile chiral diol building block characterized by its rigid cyclopentane backbone and two hydroxyl groups in a trans configuration. This compound matters for its ability to impart specific stereochemistry and conformational rigidity to complex molecules, which is critical for modulating their biological activity and physical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, chiral ligand development, and as a precursor for advanced materials.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Chiral Ligand & Catalyst Synthesis: Used to construct sophisticated ligands for asymmetric catalysis, enhancing the enantioselectivity of critical synthetic transformations.
• Agrochemical Development: Employed as a building block for novel herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for efficacy.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polyesters and polyurethanes with tailored thermal and mechanical properties.
• Flavor & Fragrance Chemistry: Utilized in the synthesis of complex odorants and flavoring agents that require precise stereochemical control.
• Academic & Industrial Research: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	(+/-)-trans-1,3-Cyclopentanediol
CAS No.	16326-98-0
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	trans-1,3-Cyclopentanediol; (±)-trans-1,3-Cyclopentanediol; 1,3-Cyclopentanediol, trans-; rac-trans-1,3-Cyclopentanediol; Cyclopentane-1,3-diol, trans-; DL-trans-1,3-Cyclopentanediol; 1,3-Dihydroxycyclopentane (trans); NSC 403697
EINECS	Contact for details

Quality Control

Our (+/-)-trans-1,3-Cyclopentanediol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99:1 trans/cis ratio
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.