Description

2-{[3-(Trifluoromethyl)Phenyl]Thio}Benzoic Acid is a high-value organosulfur compound featuring a benzoic acid core linked to a trifluoromethylphenyl group via a thioether bridge. This unique structure makes it a critical advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's trifluoromethyl and thioether motifs are key pharmacophores that can enhance metabolic stability and binding affinity in target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in areas like kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves lipophilicity and biological activity.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials with tailored properties.
• Ligand Synthesis: Utilized for constructing complex ligands in catalysis and coordination chemistry, leveraging the electron-withdrawing nature of the trifluoromethyl group.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-{[3-(Trifluoromethyl)Phenyl]Thio}Benzoic Acid
CAS No.	16174-88-2
Molecular Formula	C14H9F3O2S
Molecular Weight	298.28 g/mol
Synonyms	2-[(3-Trifluoromethylphenyl)thio]benzoic acid; 2-[[3-(Trifluoromethyl)phenyl]thio]benzoic Acid; Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]thio]-; 2-(3-Trifluoromethylphenylthio)benzoic acid; α-(3-Trifluoromethylphenylthio)benzoic acid; 2-(α,α,α-Trifluoro-m-tolylthio)benzoic acid; m-Trifluoromethylphenyl 2-carboxyphenyl sulfide
EINECS	Contact for details

Quality Control

Our 2-{[3-(Trifluoromethyl)Phenyl]Thio}Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.