Description

5-(Benzyloxy)-2-Hydroxybenzoic Acid is a versatile aromatic carboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and fine chemical synthesis. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with salicylate or benzyl-protected phenol motifs.
• Organic Synthesis Reagent: Used in coupling reactions, esterifications, and as a precursor for more complex benzoic acid derivatives in research laboratories.
• Agrochemical Development: Intermediate in the production of herbicides, fungicides, and plant growth regulators that utilize phenolic acid structures.
• Material Science Research: Potential monomer or modifier in the development of specialized polymers, coatings, and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes that target specific biological pathways.
• Academic & Industrial R&D: Serves as a standard or starting material for methodological development and scale-up studies in process chemistry.

Basic Information

Product Name	5-(Benzyloxy)-2-Hydroxybenzoic Acid
CAS No.	16094-44-3
Molecular Formula	C14H12O4
Molecular Weight	244.24 g/mol
Synonyms	2-Hydroxy-5-(phenylmethoxy)benzoic Acid; 5-Benzyloxysalicylic Acid; Salicylic Acid 5-Benzyl Ether; Benzylic Acid Derivative; 5-O-Benzylsalicylic Acid; 5-(Benzyloxy)salicylic Acid; 2-Hydroxy-5-benzyloxybenzoic Acid; NSC 403714
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2-Hydroxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.