Description

(S)-(-)-Propylene Oxide is a high-purity, chiral epoxide compound essential for the synthesis of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs). Its specific stereochemistry is critical for producing compounds with targeted biological activity and desired pharmacokinetic profiles. This product is primarily required by the pharmaceutical, agrochemical, and specialty chemical industries for advanced research and manufacturing processes.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiopure drugs, including β-blockers, antivirals, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where stereochemistry affects efficacy and environmental safety.
• Specialty Polymer Precursor: Serves as a monomer for creating optically active polymers with specific material properties for advanced coatings and materials.
• Fine Chemical Synthesis: Employed in asymmetric synthesis and ring-opening reactions to introduce the propylene oxide moiety with high enantioselectivity.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands and catalysts for asymmetric catalysis in research and industrial processes.
• Flavor and Fragrance Industry: Intermediate for the synthesis of specific chiral flavor and aroma compounds.

Basic Information

Product Name	(S)-(-)-Propylene Oxide
CAS No.	16088-62-3
Molecular Formula	C3H6O
Molecular Weight	58.08 g/mol
Synonyms	(S)-Propylene Oxide; (S)-(-)-Methyloxirane; (S)-1,2-Epoxypropane; L-Propylene Oxide; (-)-(S)-Propylene Oxide; (S)-PO; (2S)-2-Methyloxirane; (S)-Propene Oxide
EINECS	240-202-3

Quality Control

Our (S)-(-)-Propylene Oxide is manufactured under strict quality systems to ensure high enantiomeric purity and chemical integrity. Each batch is characterized by chiral GC or HPLC to confirm identity and optical purity. We provide comprehensive Certificates of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) and keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Specific Rotation [α]D20	-15° to -18° (c=1, CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.