Description

4(3H)-Quinazolinone, 6-Chloro-8-Methoxy-5-Methyl-2-Phenyl- is a high-purity, synthetically derived quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a reliable and structurally defined building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is essential for B2B customers in the pharmaceutical, agrochemical, and fine chemical sectors who require consistent quality and scalable supply for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core structure.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in custom synthesis and contract manufacturing.
• Academic & R&D: Employed in university and institutional laboratories for medicinal chemistry research and structure-activity relationship (SAR) studies.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in manufacturing.

Basic Information

Product Name	4(3H)-Quinazolinone, 6-Chloro-8-Methoxy-5-Methyl-2-Phenyl-
CAS No.	16081-83-7
Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74 g/mol
Synonyms	6-Chloro-8-methoxy-5-methyl-2-phenyl-4(3H)-quinazolinone; 6-Chloro-8-methoxy-5-methyl-2-phenylquinazolin-4(3H)-one; 2-Phenyl-6-chloro-8-methoxy-5-methyl-4(3H)-quinazolinone; 6-Chloro-8-methoxy-5-methyl-2-phenyl-3,4-dihydroquinazolin-4-one; Quinazolin-4(3H)-one, 6-chloro-8-methoxy-5-methyl-2-phenyl-; 16081-83-7; 6-Chloro-8-methoxy-5-methyl-2-phenylquinazolinone
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 6-Chloro-8-Methoxy-5-Methyl-2-Phenyl- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.