Description

1,4-Benzoquinone-Dnph (Mono) is a high-purity chemical derivative of 1,4-benzoquinone, specifically its 2,4-dinitrophenylhydrazone (DNPH) adduct. This compound serves as a critical analytical standard and reagent for the selective detection and quantification of carbonyl compounds, particularly quinones and reactive aldehydes. It is essential for research and quality control laboratories in the pharmaceutical, environmental monitoring, and advanced material synthesis sectors. The product is supplied with a CAS Number of 16081-15-5.

Application

• Analytical Chemistry Standard: Primary use as a certified reference material (CRM) for calibrating HPLC, LC-MS, and UV-Vis instruments in carbonyl compound analysis.
• Derivatization Reagent: For the pre-column derivatization of 1,4-benzoquinone and related quinoid structures to enhance detection sensitivity and specificity in complex matrices.
• Pharmaceutical Impurity Profiling: Used in method development and validation to identify and quantify quinone-based impurities or degradation products in active pharmaceutical ingredients (APIs).
• Environmental Analysis: Employed in monitoring airborne carbonyls or quinone pollutants by derivatizing samples onto DNPH-coated cartridges for subsequent analysis.
• Organic Synthesis Intermediate: Serves as a protected or functionalized quinone building block in the synthesis of specialized dyes, pigments, and photoactive compounds.
• Biochemical Research: Utilized in studies of oxidative stress and redox biology as a tool to trap and measure specific reactive carbonyl species generated in biological systems.

Basic Information

Product Name	1,4-Benzoquinone-Dnph (Mono)
CAS No.	16081-15-5
Molecular Formula	C12H8N4O5
Molecular Weight	288.22 g/mol
Synonyms	p-Benzoquinone 2,4-dinitrophenylhydrazone; 1,4-Benzoquinone DNPH; 2,4-Dinitrophenylhydrazone of p-benzoquinone; Quinone DNPH; 2,5-Cyclohexadiene-1,4-dione, 2-(2,4-dinitrophenyl)hydrazone; p-Quinone DNPH derivative; BQ-DNPH
EINECS	Contact for details

Quality Control

Our 1,4-Benzoquinone-Dnph (Mono) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by FT-IR and melting point determination, to ensure it meets exacting standards for use as an analytical reagent. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.