Description

6-Iodoquinazolin-4-One is a halogenated quinazolinone derivative, a versatile and valuable heterocyclic building block in advanced organic synthesis. Its core structure makes it a critical intermediate for developing novel pharmaceutical compounds, particularly kinase inhibitors and other biologically active molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides based on the quinazolinone core.
• Material Science: Potential building block for creating specialty polymers or organic electronic materials with unique properties.
• Academic Research: Employed in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing client-specific compounds.

Basic Information

Product Name	6-Iodoquinazolin-4-One
CAS No.	16064-08-7
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	4(3H)-Quinazolinone, 6-iodo-; 6-Iodo-4-quinazolinone; 6-Iodo-4(3H)-quinazolinone; 6-Iodoquinazolin-4(3H)-one; Quinazolin-4-one, 6-iodo-; 6-Iodo-4-hydroxyquinazoline
EINECS	Contact for details

Quality Control

Our 6-Iodoquinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.