Description

7-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol is a high-purity, polycyclic aromatic hydrocarbon (PAH) derivative of significant research interest. This compound is a key intermediate in the study of metabolic activation pathways and the formation of DNA adducts for certain carcinogenic PAHs. It is primarily utilized by research institutions and pharmaceutical companies engaged in toxicology, cancer research, and environmental health sciences. The product is supplied with a guaranteed Certificate of Analysis to ensure reliability for sensitive analytical and experimental applications.

Application

• Biochemical Research: Critical intermediate in the investigation of benz(a)anthracene metabolism and carcinogenic mechanisms.
• Toxicology Studies: Used as a standard or reference compound in studies assessing the genotoxicity and metabolic pathways of polycyclic aromatic hydrocarbons.
• Environmental Analysis: Serves as an analytical standard for detecting and quantifying PAH metabolites in environmental and biological samples.
• Cancer Research: Employed in laboratory studies to understand DNA damage and adduct formation related to specific chemical carcinogens.
• Metabolic Pathway Elucidation: A tool for studying the enzymatic dihydrodiol formation and subsequent reactions in xenobiotic metabolism.
• Analytical Method Development: Used to develop and validate sensitive analytical methods, such as HPLC-MS or GC-MS, for PAH metabolite detection.

Basic Information

Product Name	7-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol
CAS No.	16053-72-8
Molecular Formula	C21H16O3
Molecular Weight	316.35 g/mol
Synonyms	7-(Hydroxymethyl)benz[a]anthracene-8,9-dihydrodiol; 7-Hydroxymethyl-BA-8,9-diol; 8,9-Dihydro-8,9-dihydroxy-7-(hydroxymethyl)benz[a]anthracene; BA-7-CH2OH-8,9-dihydrodiol; 7-HMBA-8,9-dihydrodiol; Benz(a)anthracene-7-hydroxymethyl-8,9-dihydrodiol; 7-Hydroxymethylbenzanthracene dihydrodiol
EINECS	Contact for details

Quality Control

Our 7-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and analytical results is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive (store away from light). For long-term storage, consider keeping the container under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.