Description

3-Hydroxy-Cyclobutanon is a versatile and synthetically valuable four-membered cyclic ketone bearing a hydroxyl substituent. This unique structural motif makes it a crucial chiral building block and intermediate in advanced organic synthesis, particularly for constructing complex, strained ring systems. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other bioactive molecules with constrained geometries.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and monomers with unique thermal or mechanical properties derived from the strained cyclobutane ring.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in ring-expansion and stereoselective transformation reactions.
• Fragrance and Flavor Intermediate: Potential use in the synthesis of specialty aroma chemicals with novel olfactory profiles.

Basic Information

Product Name	3-Hydroxy-Cyclobutanon
CAS No.	15932-93-1
Molecular Formula	C4H6O2
Molecular Weight	86.09 g/mol
Synonyms	3-Hydroxycyclobutanone; Cyclobutanone, 3-hydroxy-; 3-Oxocyclobutanol; 3-Hydroxy-1-cyclobutanone; Hydroxycyclobutanone; 3-Hydroxycyclobutan-1-one
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-Cyclobutanon is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles against our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.