Description

[(2R,3R,4R,5R)-2,3,4,5,6-Pentahydroxyhexoxy]Phosphonic Acid is a high-purity, stereochemically defined phosphonic acid derivative of a hexose sugar. This compound is valued for its role as a key chiral intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor for the synthesis of nucleoside analogs, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used in developing novel, targeted pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Ligand Synthesis: Acts as a starting material for creating complex, multi-dentate chelating agents and catalysts used in asymmetric synthesis.
• Bioconjugation Chemistry: Utilized for modifying biomolecules (e.g., peptides, sugars) by introducing a phosphonic acid functional group for labeling or altering physicochemical properties.
• Material Science: Investigated for the development of functionalized surfaces, metal-organic frameworks (MOFs), and polymers where specific sugar-phosphonate interactions are desired.

Basic Information

Product Name	[(2R,3R,4R,5R)-2,3,4,5,6-Pentahydroxyhexoxy]Phosphonic Acid
CAS No.	15806-48-1
Molecular Formula	C6H15O9P
Molecular Weight	262.16 g/mol
Synonyms	D-Glucitol, 1-deoxy-1-(phosphonooxy)-, (1S)-; 1-Deoxy-1-(phosphonooxy)-D-glucitol; D-Glucitol 1-(dihydrogen phosphate); (1S)-1-Deoxy-1-(phosphonooxy)glucitol; Phosphoric acid mono[(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl] ester; Hexitol phosphonic acid derivative
EINECS	Contact for details

Quality Control

Every batch of [(2R,3R,4R,5R)-2,3,4,5,6-Pentahydroxyhexoxy]Phosphonic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.