Description

Ribofuranose (7Ci,8Ci,9Ci) CAS NO 15761-67-8 is a fundamental monosaccharide derivative, specifically a furanose form of ribose, which serves as a critical building block in nucleic acid chemistry and glycoscience. Its value lies in its role as a versatile chiral synthon and precursor for the synthesis of nucleosides, nucleotides, and various bioactive carbohydrate derivatives. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutics, diagnostic probes, and advanced biomaterials.

Application

• Nucleoside/Nucleotide Synthesis: A key chiral starting material for the chemical and enzymatic production of ribonucleosides, their analogs, and modified nucleotides.
• Pharmaceutical Intermediates: Used in the research and development of antiviral agents (e.g., nucleoside reverse transcriptase inhibitors), anticancer prodrugs, and mRNA vaccine components.
• Bioconjugation & Labeling: Serves as a scaffold for creating labeled sugars or for incorporating sugar moieties into antibodies, proteins, or other biomolecules for targeted delivery or imaging.
• Glycochemistry & Glycobiology Research: Employed in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics to study carbohydrate-protein interactions.
• Fine Chemical Synthesis: Acts as a chiral pool reagent for the asymmetric synthesis of natural products and other value-added specialty chemicals.
• Diagnostic Reagent Development: Utilized in formulating enzymatic assay kits and other in vitro diagnostic (IVD) reagents that require high-purity sugar substrates.

Basic Information

Product Name	Ribofuranose (7Ci,8Ci,9Ci)
CAS No.	15761-67-8
Molecular Formula	C5H10O5
Molecular Weight	150.13 g/mol
Synonyms	Ribofuranose; D-Ribofuranose; Ribose, furanose form; (3R,4S,5R)-5-(Hydroxymethyl)oxolane-2,3,4-triol; 15761-67-8; D-(-)-Ribofuranose; β-D-Ribofuranose; α-D-Ribofuranose
EINECS	Contact for details

Quality Control

Our Ribofuranose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial standards (USP, EP) and regulatory frameworks (REACH, FDA DMF) as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.