Description

(E)-4',β-Dichloroacrylophenone is a high-purity, specialized organic intermediate characterized by its distinct α,β-unsaturated ketone structure with chlorine substituents. This compound is valued for its reactivity as a key building block in the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those requiring a halogenated chalcone or propenone scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile electrophile in Michael additions, cyclization reactions, and cross-coupling chemistry for creating complex heterocycles.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized in the design of molecular probes to study enzyme inhibition and biological pathways.

Basic Information

Product Name	(E)-4',β-Dichloroacrylophenone
CAS No.	15724-88-6
Molecular Formula	C9H6Cl2O
Molecular Weight	201.05 g/mol
Synonyms	1-(4-Chlorophenyl)-3-(2-chlorophenyl)-2-propen-1-one; (E)-1,2-Bis(4-chlorophenyl)-2-propen-1-one; 4,4'-Dichlorochalcone; (E)-4,4'-Dichlorochalcone; NSC 403914; (E)-1,3-Bis(4-chlorophenyl)prop-2-en-1-one; (E)-3-(4-Chlorophenyl)-1-(4-chlorophenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Every batch of (E)-4',β-Dichloroacrylophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, GC, or NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.