Description

Toluene, [14C] CAS NO 15644-74-3 is a carbon-14 radiolabeled isotopologue of toluene, a fundamental aromatic hydrocarbon solvent. This compound is essential for advanced research and development, providing a critical tool for precise metabolic, environmental, and pharmacokinetic studies through its radioactive tracer properties. It is primarily utilized by scientists and quality control professionals in the pharmaceutical, agrochemical, and environmental science industries for applications requiring high-sensitivity detection and pathway elucidation.

Application

• Metabolic Pathway Tracing in pharmaceutical and agrochemical research to study drug and pesticide biotransformation.
• Environmental Fate Studies to monitor the degradation, adsorption, and transport of toluene and related compounds in ecosystems.
• Pharmacokinetic Analysis for the quantitative assessment of absorption, distribution, metabolism, and excretion (ADME) of new chemical entities.
• Biochemical Reaction Mechanism investigations to identify intermediate products and reaction pathways.
• Quality Control and Method Development as an internal standard or tracer in advanced analytical techniques like LC-MS.
• Material Science Research for studying polymerization mechanisms and the incorporation of monomers in polymer matrices.

Basic Information

Product Name	Toluene, [14C]
CAS No.	15644-74-3
Molecular Formula	C714CH8 or C6H514CH3
Molecular Weight	~93.15 g/mol (exact mass depends on 14C position)
Synonyms	Methyl-14C-benzene; Toluene-14C; [14C]Toluene; Radiolabeled Toluene; Carbon-14 Labeled Toluene; Phenyl-14C-methane; Toluene (ring-14C); Toluene (methyl-14C)
EINECS	Contact for details

Quality Control

Every batch of Toluene, [14C] is manufactured and analyzed under strict quality systems to ensure radiochemical purity, chemical purity, and specific activity meet the precise requirements of research applications. Comprehensive analysis via HPLC with radiometric detection is standard. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting exact specifications, including radionuclidic purity and expiration date.

Storage

Preserve in a tightly closed container, protected from light. Store in a dedicated, well-ventilated area for radioactive materials at the recommended temperature (typically 2-8°C or as specified on the label) to maintain stability. Due to its high volatility, ensure containers are securely sealed. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Assay (Radiochemical Purity)	≥ 98%
Specific Activity	Customizable (mCi/mmol)
Chemical Purity (HPLC)	≥ 99%
Solvent	Specified on COA (e.g., Toluene, Benzene)
Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.