Description

4-Acetoxymethylbenzoic Acid is a versatile benzoic acid derivative characterized by an acetoxymethyl functional group, serving as a key synthetic intermediate in advanced organic synthesis. This compound is valued for its role in constructing more complex molecular architectures, particularly in pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as prodrug synthesis and polymer modification.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for prodrug strategies where the acetoxymethyl group aids in bioavailability.
• Fine Chemical Synthesis: Used in research and development for creating novel compounds with potential biological activity in agrochemicals and material science.
• Polymer Chemistry: Acts as a monomer or functionalization agent for introducing benzoic acid moieties into polymer backbones, modifying material properties.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the development of advanced organic electronic materials and liquid crystal displays.
• Cross-coupling Reactions: The carboxylic acid group allows for further derivatization, making it a substrate in palladium-catalyzed and other metal-mediated coupling reactions.
• Protecting Group Chemistry: The acetoxymethyl moiety can be utilized as a protecting group for alcohols or carboxylic acids in multi-step synthetic pathways.

Basic Information

Product Name	4-Acetoxymethylbenzoic Acid
CAS No.	15561-46-3
Molecular Formula	C10H10O4
Molecular Weight	194.18 g/mol
Synonyms	4-(Acetoxymethyl)benzoic Acid; p-(Acetoxymethyl)benzoic Acid; Benzoic acid, 4-(acetoxymethyl)-; 4-Carboxyphenylmethyl acetate; Acetic acid 4-carboxybenzyl ester; (4-Carboxybenzyl) acetate; p-Carboxybenzyl alcohol acetate
EINECS	Contact for details

Quality Control

Our 4-Acetoxymethylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Single impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.