Description

2-Bromo-2-Cyano-N,n-Dimethylacetamide is a versatile brominated cyanoacetamide derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique reactivity profile, enabling the introduction of both bromo and cyano functional groups in a single molecular framework, which is essential for constructing complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing heterocyclic cores like pyrazoles, imidazoles, and triazoles.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways, cyclization reactions, and as a scaffold in medicinal chemistry programs.
• Specialty Polymer Modification: Can be employed to introduce functional groups into polymer chains, altering physical properties for advanced material applications.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chelating agents or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-2-Cyano-N,n-Dimethylacetamide
CAS No.	15430-62-3
Molecular Formula	C6H9BrN2O
Molecular Weight	205.06 g/mol
Synonyms	2-Bromo-2-cyano-N,N-dimethylacetamide; N,N-Dimethyl-2-bromo-2-cyanoacetamide; Bromocyano-N,N-dimethylacetamide; Acetamide, 2-bromo-2-cyano-N,N-dimethyl-; α-Bromo-α-cyano-N,N-dimethylacetamide; 2-Bromo-2-cyano-N,N-dimethylacetamide; 15430-62-3; Bromocyanoacetic acid dimethylamide
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Cyano-N,n-Dimethylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases, strong oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.