Description

Bis-(Toluene-4-Sulfonyl)-Methane is a specialized organic sulfone compound, widely recognized as a versatile building block and reagent in advanced chemical synthesis. Its core value lies in its ability to act as a methylene transfer agent and a key precursor for the preparation of complex molecules, including pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research and development laboratories, as well as production facilities in the fine chemical and pharmaceutical sectors seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonyl or methylene-bridged structures.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where specific sulfone functionalities are required.
• Polymer Chemistry: Serves as a cross-linking agent or monomer modifier in the production of specialty polymers with enhanced thermal or chemical resistance.
• Organic Synthesis Reagent: Employed as a methylene dianion equivalent or a sulfonylating agent in complex organic transformations, including C-C bond formation.
• Material Science Research: Utilized in the development of novel organic electronic materials and ligands for catalytic systems.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and colorants.

Basic Information

Product Name	Bis-(Toluene-4-Sulfonyl)-Methane
CAS No.	15310-28-8
Molecular Formula	C15H16O4S2
Molecular Weight	324.41 g/mol
Synonyms	Bis(p-Toluenesulfonyl)methane; Di-p-tolylsulfonylmethane; Methane, bis(p-tolylsulfonyl)-; 1,1'-[Methylenebis(sulfonyl)]bis[4-methylbenzene]; p-Toluenesulfonylmethyl p-toluenesulfonate; TSMI; (4-Methylphenyl)sulfonyl-(4-methylphenyl)sulfonylmethane
EINECS	Contact for details

Quality Control

Our Bis-(Toluene-4-Sulfonyl)-Methane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring a reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider using desiccants to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.