Description

o-Benzyl-L-Threonine Benzyl Ester Oxalate is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial chiral building block for the controlled construction of peptides and other complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate L-threonine residues with orthogonal protecting groups.
  li>Bioconjugation & Labeling: Facilitates the site-specific modification of peptides and proteins for drug delivery systems and diagnostic probes.- Chemical Biology Research: Employed in the synthesis of peptide libraries for screening and structure-activity relationship (SAR) studies.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A fundamental reagent for synthetic organic chemistry laboratories exploring new methodologies and complex natural product synthesis.

Basic Information

Product Name	o-Benzyl-L-Threonine Benzyl Ester Oxalate
CAS No.	15260-11-4
Molecular Formula	C20H23NO6 • C2H2O4
Molecular Weight	469.46 g/mol
Synonyms	L-Threonine, O-benzyl-, benzyl ester, oxalate (1:1); Benzyl L-threoninate benzyl ether oxalate; O-Benzyl-L-threonine benzyl ester oxalate salt; (2S,3R)-2-Amino-3-(benzyloxy)butanoic acid benzyl ester oxalate; H-Thr(Bzl)-OBzl • Oxalic acid; Protected L-Threonine benzyl ester oxalate; Thr(Bzl)-OBzl oxalate
EINECS	Contact for details

Quality Control

Our o-Benzyl-L-Threonine Benzyl Ester Oxalate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. For long-term storage, consider desiccant use and a nitrogen atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.