Description

2-Hydroxy-4-Oxo-1H-Quinoline-3-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and advanced materials. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Coordination Chemistry: Serves as a ligand or precursor for metal-organic frameworks (MOFs) and catalytic complexes due to its chelating properties.
• Organic Synthesis Building Block: Employed in cyclization reactions and heterocyclic chemistry to create fused ring systems.
• Material Science: Investigated for the development of organic semiconductors, fluorescent dyes, and photostable materials.
• Biochemical Research: Used as a scaffold for designing enzyme inhibitors and molecular probes in biochemical assays.

Basic Information

Product Name	2-Hydroxy-4-Oxo-1H-Quinoline-3-Carbonitrile
CAS No.	15000-43-8
Molecular Formula	C10H6N2O2
Molecular Weight	186.17 g/mol
Synonyms	2-Hydroxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile; 3-Cyano-2-hydroxy-4(1H)-quinolinone; 2-Hydroxy-4(1H)-quinolinone-3-carbonitrile; 3-Cyano-2-hydroxyquinolin-4(1H)-one; 2-Hydroxy-4-quinolone-3-carbonitrile; 4-Hydroxy-3-cyano-2-quinolone; 2-Hydroxy-4-oxo-1H-quinoline-3-carbonitrile; Quinoline-3-carbonitrile, 2-hydroxy-4-oxo-1H-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-Oxo-1H-Quinoline-3-Carbonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Specifications can be tailored to meet the requirements of research, development, and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.