Description

3-Chloro-4-Hydroxy-1H-Quinolin-2-One is a high-purity, synthetically valuable quinolinone derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for creating complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various disease pathways.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional additive in the synthesis of specialty polymers, dyes, or organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry studies and structure-activity relationship (SAR) exploration.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic systems through further functionalization reactions.

Basic Information

Product Name	3-Chloro-4-Hydroxy-1H-Quinolin-2-One
CAS No.	14933-25-6
Molecular Formula	C9H6ClNO2
Molecular Weight	195.60 g/mol
Synonyms	3-Chloro-4-hydroxy-2(1H)-quinolinone; 3-Chloro-4-hydroxyquinolin-2(1H)-one; 4-Hydroxy-3-chloro-1H-quinolin-2-one; 3-Chloro-4-hydroxy-1H-quinol-2-one; 2-Quinolinone, 3-chloro-4-hydroxy-; 3-Chloro-4-hydroxy-2-quinolone; 3-Chloro-4-hydroxycarbostyril
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-1H-Quinolin-2-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.