Description

Acetamide, 2,2,2-Trifluoro-n-(2,4,6-Trimethylphenyl)- is a specialized fluorinated acetamide derivative characterized by its unique trifluoromethyl and mesityl substituents. This compound is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and crop protection industries seeking to introduce specific fluorinated motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoroacetamide or mesityl-protected amine group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers and advanced materials with specific thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Studies: A valuable reagent for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and agrochemical discovery programs.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(2,4,6-Trimethylphenyl)-
CAS No.	14818-54-3
Molecular Formula	C11H12F3NO
Molecular Weight	231.22 g/mol
Synonyms	2,2,2-Trifluoro-N-(2,4,6-trimethylphenyl)acetamide; N-Mesityl-2,2,2-trifluoroacetamide; α,α,α-Trifluoro-N-mesitylacetamide; 2,2,2-Trifluoroacetmesidide; Trifluoroacetylmethylaniline; N-(2,4,6-Trimethylphenyl)-2,2,2-trifluoroacetamide; Acetamide, 2,2,2-trifluoro-N-(2,4,6-trimethylphenyl)-; TFMAA (common abbreviation)
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-n-(2,4,6-Trimethylphenyl)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results for purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.